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Gefitinibs single-agent activity in a group consisting of pretreated NSCLC patients is confirmed. Side-effects of gefitinib were mild. Prolonged survival was associated with good PS and less significantly with a never-smoking history, female gender and histology. Additional studies on mechanisms of tumor control and selection of target populations for this remarkable new drug are warranted.
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Cancer screening for older women remains an area of active investigation. One current recommendation is to perform screening for individuals with a life expectancy of 5 years or more, as early detection of tumor in these individuals is more likely to have an impact on survival. In this cross-sectional population based study from California, it is apparent that screening is currently applied to older women without consideration of health status. Thus, for many, mammography and Pap smears are being obtained with little hope of benefit.
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The strength of a clinicians recommendation for patient care is greatest in data generated through carefully conducted experimental studies. In many cases, this quality of data is generated from randomized clinical trials where a novel intervention is compared against some standard of care. When properly designed and conducted, positive or negative results will generally provide convincing evidence to support a change in that standard or refute one, particularly if the outcomes are independently confirmed.
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If you could find a way to ensure that medications were absorbed quicker with less pain and no risk of a needlestick injury, would you do this for your patients? Intranasal drug delivery offers all of these benefits, but the vast majority of EDs dont use it, according to Timothy Wolfe, MD, associate professor of emergency medicine at University of Utah School of Medicine in Salt Lake City.
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If an unconscious man was rushed to your ED after a terrorist attack with possible exposure to biological or chemical agents, would you know exactly how to decontaminate and treat this patient? What if your patient was a 3-year-old?
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Are dirty meal trays a common sight in your ED? By switching to a disposable tray system, the ED at Paradise Valley Hospital in National City, CA, was able to save $300 a month, reports Stephanie J. Baker, RN, BSN, CEN, MBA/HCM, director of emergency services.
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Many of the tourniquets that come in prepackaged intravenous (IV) start kits are not adequate for difficult-start patients, says Linell Jones, RN, BSN, CEN, ED nurse at Good Samaritan Hospital in Puyallup, WA.
